Stably Expressing Reporter Cell Lines

Most of invivogen s cell lines are engineered to stably express an inducible secreted reporter gene.

Stably expressing reporter cell lines.

Reporter cell lines invivogen offers a large panel of cell lines engineered to provide simple rapid and reliable monitoring of innate immunity specific signaling pathways. Molecular carcinogenesis 2016 doi. The reporter gene is stably integrated in the target cell genome to ensure stable reporter gene expression during continued passaging in culture. Each of our reporter stable cell lines has been transduced to stably express a fluorescent or luminescent reporter molecule.

Hek293 tcf lef luciferase reporter stable cell line sl 0015. Nfkb luciferase reporter a549 stable cell lines sl 0014. Signosis has developed nrf2 reporter mcf7 stable cell line that has been stably transfected with pta nrf2 luciferase reporter vector which contains 8 repeats of nrf2 binding sites a minimal promoter upstream of the firefly luciferase coding region along with a g418 expression vector. We use high efficiency lentiviral vector transduction methods to generate our stable reporter gene cell lines.

We offer two reporter systems relying either on the secreted embryonic alkaline phosphatase seap or the lucia luciferase. Alcohol promotes migration and invasion of triple negative breast cancer cells through activation of p38 mapk and jnk m zhao ew howard ab parris z guo q zhao x yang. Our cells stably express one or two reporter proteins the secreted embryonic alkaline phosphatase seap and or the lucia luciferase.