Stem Cell Treatment For Spine Injury

Injury and the consequence of injury disrupts the turning over of cells basically because of reduced electrical activity which oligodendrocytes depend on for survival and myelination.

Stem cell treatment for spine injury.

I m convinced that endogenous stem cells in the spinal cord those naturally born there by the million every hour even in spinal cord injured adults. Windebank m d is moving into phase 2 clinical trials. The research discusses the experience related to the first case in a phase i safety study of mesenchymal stem cell treatment for spinal cord injury. Study participants must be age 18 or older and have experienced traumatic spinal cord injury within the past year.

In celltop phase 2 40 patients will be randomized to receive stem cell treatment or best medical management. While the concept seems appealing i am concerned that patients may be drawn in by hope and hype without having the full picture of the science. In fact as of january of 2020 the fda hasn t approved any stem cell therapies for this purpose. So these treatments are not available in the mainstream medical market.

We have demonstrated that stem cell therapy is safe in people with als. Patients randomized to the medical management arm will eventually cross over to the stem cell arm. The reason for this ambiguity is that stem cell therapy for spinal cord injuries is in its infancy as a treatment. What is a degenerative disc and the degenerative cascade.

A mayo clinic neurologic surgeon and the lead author cautions that each patient is different so it s too early to consider stem cell therapies as a treatment or cure for. Since their discovery in 1998 they have been used in thousands of studies to one day cure paralysis but there is still no cure for those with chronic injuries despite this scientists have come a long way especially in recent years. Food and drug administration has even expressed. Supportive therapies such as rna therapy iv laser iv oxygen iv nutrition shockwave therapy physiotherapy and spinal laser therapy are administered alongside stem cell treatment for spinal cord injury sci for an enhanced outcome.

The therapy developed in the regenerative neurobiology laboratory under the direction of anthony j. Shim explains how a disc goes through the degenerative cascade. Could stem cell therapy be an answer for disc disease. Windebank is also involved in the new clinical trial for people with traumatic spinal cord injuries.